Growth and differentiation factors conveyed through an innovative molecular laser

MD Pier Mario Biava together with dr. Enrico Bonizzoni have developed an innovative patented active drug transport system based on the principle of particle acceleration.

  • The laser is an EU certified medical device with class 2 laser

  • Both the research and the construction are done in Milan by expert and qualified technicians

  • After certification, the laser was extensively tested for 2 years with growth and differentiation factors extracted from Zebrafish embryos

The laser is now ready for distribution together with specific cryo-applicator that may contain growth or differentiation factors taken from the evolutionary stages of the Zebrafish embryo. We called the new laser Criopass Laser, and its usage Criopass Therapy.

  • The new molecular pharmaco-kinetics uses a particular mechanism in which the drug, inserted in a special cryo-applicator, is frozen at (-18 °) and subsequently coupled to a laser source from which it receives the energy necessary to penetrate the skin barrier and transport the molecules of the active ingredient in depth to reach the sites of use.

  • The Criopass software allows you to automatically set all the laser parameters to convey the active ingredient to the desired depth

Criopass Therapy is based on a physical process of acceleration of particles

  • The photonic flux generated by a laser beam is conveyed inside a cryo applicator where it meets the drug molecules imprisoned in the frozen crystal lattice
  • The drug molecules thus charged, melting at the ice / skin interface, being no longer retained by the frozen interface, release the energy accumulated in the form of kinetic energy which causes the molecule itself to accelerate gravitationally which allows it to pass through the skin membrane, till it reaches the desired site.
  • The next step uses a laser scanning on the skin to optimize the delivery of the drug previously placed at the desired level. In particular, it was found that at the level of structures such as cartilages, this procedure provides a valid tool for creating significant drug concentrations in the site to be treated, which is difficult to reach with traditional drug administration methods.

Criopass Therapy is based on a physical process of acceleration of particles:

  • The photonic flux generated by a laser beam is conveyed inside a cryo applicator where it meets the drug molecules imprisoned in the frozen crystal lattice

Criopass Therapy is based on a physical process of acceleration of particles

  • The photonic flux generated by a laser beam is conveyed inside a cryo applicator where it meets the drug molecules imprisoned in the frozen crystal lattice
  • The drug molecules thus charged, melting at the ice / skin interface, being no longer retained by the frozen interface, release the energy accumulated in the form of kinetic energy which causes the molecule itself to accelerate gravitationally which allows it to pass through the skin membrane, till it reaches the desired site.
  • The drug molecules thus charged, melting at the ice / skin interface, being no longer retained by the frozen interface, release the energy accumulated in the form of kinetic energy which causes the molecule itself to accelerate gravitationally which allows it to pass through the skin membrane, till it reaches the desired site.
  • The next step uses a laser scanning on the skin to optimize the delivery of the drug previously placed at the desired level. In particular, it was found that at the level of structures such as cartilages, this procedure provides a valid tool for creating significant drug concentrations in the site to be treated, which is difficult to reach with traditional drug administration methods.
  • The next step uses a laser scanning on the skin to optimize the delivery of the drug previously placed at the desired level. In particular, it was found that at the level of structures such as cartilages, this procedure provides a valid tool for creating significant drug concentrations in the site to be treated, which is difficult to reach with traditional drug administration methods.

LIGHTNING SPEED

Each application with the cryapplicator takes about 4 minutes, followed by about 10 minutes with the second laser

NO DOWN TIME

In 2 years of continuous testing, the reliability was 100%. Without any interruption

AMAZING INTERFACE

The software has been designed to be user friendly. It is extremely intuitive

BOLD SECURITY

The molecular laser has proven to be able to guarantee maximum safety for the patient and the therapist

LIGHTNING SPEED

Each application with the cryapplicator takes about 4 minutes, followed by about 10 minutes with the second laser

NO DOWN TIME

In 2 years of continuous testing, the reliability was 100%. Without any interruption

AMAZING INTERFACE

The software has been designed to be user friendly. It is extremely intuitive

BOLD SECURITY

The molecular laser has proven to be able to guarantee maximum safety for the patient and the therapist

LIGHTNING SPEED

Each application with the cryapplicator takes about 4 minutes, followed by about 10 minutes with the second laser

NO DOWN TIME

In 2 years of continuous testing, the reliability was 100%. Without any interruption

AMAZING INTERFACE

The software has been designed to be user friendly. It is extremely intuitive

BOLD SECURITY

The Molecular Laser has proven to be able to guarantee maximum safety for the patient and the doctor

SCIENTIFIC PUBLICATION

Stem cell growth and differentiation factors from Zebrafish embryo and their role as epigenetic regulators in hair regeneration: results after transdermal administration using cryopass laser treatment

CRYOPASS LASER PRESENTATION

CELL REPROGRAMMING APPLIED TO REGENERATIVE AESTHETIC MEDICINE

SCIENTIFIC PUBLICATION

Transdermal administration of melatonin coupled to cryopass laser treatment as noninvasive therapy for prostate cancer

Cryopass therapy Molecular laser

The equipe of dr. Biava carry out specific treatments with the Molecular Laser. The laser is capable of delivering any type of drug or growth and differentiation factors taken from evolutionary stages from the Zebrafish embryo directly into the human body by penetrating the skin barrier and transporting the active ingredient molecules to the desired depth. The treatment is absolutely non-invasive and painless.

  • It’s ease to convey active ingredients to specific target sites, often difficult to reach using other methods. The new Molecular Laser can be used very well in the following disciplines:

    • Orthopedics
    • Physiatry
    • Gynecology
    • Dermatology
    • Neurology
    • Urology
    • Angiology
    • Sports Medicine
    • Plastic Surgery
    • Aesthetic Medicine
    • Thermal Medicine
    • Ophthalmology
    • Cardiology
    • Regenerative medicine

3 INTERNATIONAL PATENTS

EUROPEAN PATENT

FACTORS EXTRACTED FROM FISH EMBRYOS AND USE OF MIXTURES THEREOF IN THE CONTROL OF STEM CELL MULTIPLICATION AND DIFFERENTIATION

USA PATENT

FACTORS EXTRACTED FROM FISH EMBRYOS AND USE OF MIXTURES THEREOF IN THE CONTROL OF STEM CELL MULTIPLICATION AND DIFFERENTIATION

EUROPEAN PATENT

MOLECULAR LASER A MEDICAL APPARATUS FOR CUTANEOUS ADMINISTRATION OF MEDICAMENTS CONSISTING OF AN ENERGY EMITTER ACTIVE ON MOLECULES OF A MEDICAMENT

EUROPEAN PATENT

FACTORS EXTRACTED FROM FISH EMBRYOS AND USE OF MIXTURES THEREOF IN THE CONTROL OF STEM CELL MULTIPLICATION AND DIFFERENTIATION

USA PATENT

FACTORS EXTRACTED FROM FISH EMBRYOS AND USE OF MIXTURES THEREOF IN THE CONTROL OF STEM CELL MULTIPLICATION AND DIFFERENTIATION

BREVETTO EUROPEO

MOLECULAR LASER A MEDICAL APPARATUS FOR CUTANEOUS ADMINISTRATION OF MEDICAMENTS CONSISTING OF AN ENERGY EMITTER ACTIVE ON MOLECULES OF A MEDICAMENT

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CRYOPASS THERAPY WITH MOLECULAR LASER

Terapie OrtopedicheRIABILITAZIONE e TERAPIA DEL DOLOREEsperienza multicentricaDal 2015 al 2020

Multicenter prospective study carried out in the orthopedic field which includes experience on over 13,000 solvent patients treated by CRIOPASS THERAPY, divided into the main orthopedic pathologies, at the aforementioned medical offices in Milan, Busto Arsizio and Vigone. Evaluation and cross-analysis of the evaluation parameters for a more realistic interpretation of the analyzed data.

DOWNLOAD THE PRESENTATION

MADE IN ITALY

Novacell Biotech Company Srl was founded with the purpose of studying and develop integrative treatments in the field of oncology, neurodegeneration, antiaging and in general for prevention and well-being.

Novacell Biotech Company Srl was founded with the purpose of studying and develop integrative treatments in the field of oncology, neurodegeneration, antiaging and in general for prevention and well-being.

The research laboratories used by Novacell are at the forefront of aging research. Scientific innovation has led to the recognition of Novacell as a leader in the food supplements and cosmetics industry. The product formulations and technologies used allow us to reach new standards with solutions that redefine youth and make themselves evident with demonstrable results. Dr Pier Mario Biava expresses our commitment to research and development by collaborating with many international level institutes. These collaborative relationships help develop the next generation of dermo-cosmetic and nutraceutical products.

MD Pier Mario Biava on Growth and Differentiation factors:

“GROWTH and DIFFERENTIATION FACTORS they have significant biological activity, which is essential for maintaining cellular health. Some proteins are important for the life of mitochondria, others have the function of regulating the cell cycle, the immune response and so on. Therefore, the biological molecules of ROE EXTRACT are essential to keep the cells of our body in optimal health conditions and revitalize the tissues, minimizing the phenomena of aging.”

Dr. Pier Mario Biava and his team of scientists have shown that specific GROWTH and DIFFERENTIATION FACTORS increase the lifespan of cells, preventing telomere cutting and contributing to the synthesis of proteins, which stop cell aging.

MD Pier Mario Biava on Telomeres:

“Telomeres become shorter every time cells divide. When the telomere becomes too short, the chromosome reaches a critical length and can no longer replicate. This means that a cell becomes old and dies. However GROWTH and DIFFERENTIATION Factors may represent a very effective tool to promote the antagonists of cell senescence in a physiological way. The result is a healthier Cell and potentially a reversal of the aging process”.

Telomeres are essential parts of human cells that effect how we age. Telomeres are the caps at the ends of each strand of Dna that protect the chromosome.

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